By A Arimura (auth.), Hubert Vaudry, Akira Arimura (eds.)
ISBN-10: 1461349834
ISBN-13: 9781461349839
ISBN-10: 1461502438
ISBN-13: 9781461502432
Pituitary Adenylate Cyclase-Activating Polypeptide is the 1st quantity to be written at the neuropeptide PACAP. It covers all domain names of PACAP from molecular and mobile facets to physiological actions and grants for brand new healing suggestions.
Pituitary Adenylate Cyclase-Activating Polypeptide is the 20th quantity released within the Endocrine Updates ebook sequence less than the sequence Editorship of Shlomo Melmed, MD.
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Labrie F, Borgeat P, Drouin J, Beaulieu M, Lagace L, Ferland L, Raymond V. Mechanism of action of hypothalamic hormones in the adenohypophysis. Annu Rev Physiol 1979;41 :555569. Labrie F, Veilleux R, Lefevre G, Coy DH, Sueiras-Diaz J, Schally AV. Corticotropin-releasing factor stimulates accumulation of adenosine 3',5'-monophosphate in rat pituitary corticotrohs. Science 1982;216:1007-1008. Lam HC, Takahashi K, Ghatei MA, Kanse SM, Polak 1M, Bloom SR. Binding sites of a novel neuropeptide pituitary adenylate cyclase activating polypeptide in the rat brain and lung.
The localization of the human gene places it in the region which is also the locus for the craniofacial defect holoprosencephaly type 3 (HPE3). Further mapping experiments, carried out on cell lines derived from patients with HPE or HPE microforms and associated 7q deletions, have led to a redefinition of the distal extent of the HPE3 minimal critical region, originally characterized by Gurrieri et a1 (1993). The VPAC2-R gene lies within this new HPE3 minimal critical region. It has been suggested that deletion of the VPAC2-R gene is not the sole factor responsible for the HPE3 phenotype.
Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide. DNA Cell Bio 1992;11:21-30. Ohkubo S, Ogi K, Kimura C, Okazaki K, Onda H, Fujino, M. Expression of the P ACAP gene in a human neuroblastoma cell line: cDNA cloning and analyses of the upstream regulatory region. Endocrine J 1994;2:135-145. Okazaki K, Kimura C, Kosaka T, Watanabe T, Ohkubo S, Ogi K, Kitada C, Onda H, Fujino M. Expression of human pituitary adenylate cyclase activating polypeptide (P ACAP) cDNA in CHO cells and characterization of the products.
Pituitary Adenylate Cyclase-Activating Polypeptide by A Arimura (auth.), Hubert Vaudry, Akira Arimura (eds.)
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